DHH-B (dihydrohonokiol-B)

Dihydrohonokiol-B (DHH-B; 3'-(2 propenyl)-5-propyl-(1,1'-biphenyl)-2,4'-diol), which is a a partially reduced derivative of honokiol, is an effective anxiolytic-like agent in mice [Maruyama2001  🕮 ].

Do not confuse DHH-B with another chemical called diethylamino-hydroxybenzoyl hexyl benzoate which is an organic compound used in sunscreens to absorb UVA radiation.

•       [Maruyama2001]   Y Maruyama, H Kuribara, E Kishi, S T Weintraub, Y Ito. Confirmation of the anxiolytic-like effect of dihydrohonokiol following behavioural and biochemical assessments. J Pharm Pharmacol. 2001 May;53(5):721-5. PMID: 11370711 DOI: 10.1211/0022357011775848